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INDICATIONS
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Paralysis Tick Control
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Flea Control and Management of Flea Allergic Dermatitis
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Fly Nuisance on Horses
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Management of Queensland Itch
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General Purpose Insect Repellent
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Use as a Spray or Rinse
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Safe for use on pregnant and lactating animals
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REGISTERED FOR USE IN
Dogs and Horses
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4.0% Permethrin 25:75(cis:trans)
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- A highly effective insecticide and tickicide with insect repellent activity
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ACTIONS
Highly Effective Tickicide and Insecticide. In laboratory trials, a single application of PERMOXIN prevents tick attachment for over two weeks and resulted in greater than 98% flea control for 20 days.
Flea and Insect Repellent. When applied daily to flea allergic dogs, PERMOXIN repels fleas and gives relief to the pruritic dog. In fact, the high safety margin means that Permoxin can be applied as often as needed, to maintain the repellent action.
Binds to the Hair Coat. PERMOXIN utilises advanced technology which allows it to bind to clean hair and skin for long acting effectiveness. Peak activity is maintained by regular weekly top up rinses to produce saturation of the hair coat.
Resists Inactivation by Light. This ensures a longer duration of action than the natural pyrethrins which decompose rapidly on exposure to air and light.
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Dilute to 1:40 (as directed by label) in water, or methylated spirits if a rapid drying spray is required. Spray or rinse as directed.
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CONTRAINDICATIONS
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PERMOXIN is NOT to be used on cats
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EFFICACY
Although the laboratory trials show 100% control of Paralysis ticks for 13 days, it is recommended that dogs should be rinsed thoroughly every 7 days, with daily inspections for ticks to ensure good control in a clinical use situation. †
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To Confirm a Diagnosis of Flea Allergic Dermatitis (FAD)
- Spray the animal DAILY with PERMOXIN for 14 days. DO NOT use any corticosteroids or antihistamines.
- Re-examine the animal after 14 days and assess the degree of improvement in the skin (reduced erythema and new hair growth). Have the client report on the degree of reduction in pruritus.
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Interpretation of Clinical Response
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CLINICAL IMPROVEMENT
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DIAGNOSIS
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< 30%
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Reject diagnosis of FAD
Consider – Atopy, Pyoderma, Malassezia, Food Allergy etc
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~ 50%
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Fleas important but also have other factors
Consider – Atopy + FAD, Pyoderma + FAD
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> 70%
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Confirms diagnosis of FAD
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CONFIRMED FAD – Management Approach
- Advise the client on the need for environmental flea control.
- Adjust the frequency of PERMOXIN administration, to maintain control of the clinical signs of FAD. This can vary from daily to fortnightly depending on the dog’s allergic sensitivity and environmental flea population.
- If the client has difficulty applying PERMOXIN as frequently as is necessary to maintain control of the clinical signs, prednisolone (0.5mg/kg 1-3 times weekly) can be used, as required to alter the dog’s allergic response. This will allow PERMOXIN to be applied less frequently to control pruritus and thus increase owner compliance.
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References
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†
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Stone et al (1994) Efficacy of Permethrin in Controlling the Australian paralysis tick Ixodes holocyclus and the cat flea Ctenophalides felis on dogs, JSAP Vol 71 No. 3.
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